CVS Pharmacy is the largest and most direct competitor with Walgreens, and its retail pharmacy's operations currently occupy the largest market share of prescription revenues in the U.S.. [6] CVS has a similar business model to Walgreens which includes a large amount of stores that sell general merchandise, while gaining most profits from the pharmacy division.
Express Scripts is a Pharmacy Benefit Manager (PBM) that is Walgreens' second largest competitor. They compete with Walgreens using a network of retail pharmacies as well as its own system of automated pharmacies that send medications through mail order. [7]